Where can I find the protein concentration?

The protein concentration of each product is listed on the Certificate of Analysis. This value is determined for each individual lot and reflects the actual concentration (mg/mL) of the material you received.

Where can I find the recommended storage conditions?

Storage conditions are listed on both the product datasheet and the Certificate of Analysis. These recommendations are based on internal stability assessments and are intended to maintain protein integrity and activity.

What should I do if my product arrives warm, partially thawed, or damaged?

Please contact Athens Bioscience with your order number and lot number. Our technical support team will assist you promptly.

Where can I find the final buffer composition?

The final buffer formulation is provided on the Certificate of Analysis. This includes buffer components, pH, and whether the product was supplied as a liquid or lyophilized powder.

Lipoproteins, Intermediate Density

Name: Lipoproteins, Intermediate Density
SKU: 12-16-090412-1MG
Availability: InStock

Product Description

Role of protein in biology

Intermediate-density lipoprotein (IDL) is a key component of the endogenous lipid transport system, formed as a metabolic product when very low-density lipoprotein (VLDL) is hydrolyzed by lipoprotein lipase in peripheral tissues. IDL particles are enriched in both triglycerides and cholesterol esters and contain apolipoproteins B-100 and E, which are crucial for their structural integrity and for mediating interactions with cellular receptors. Through the action of cholesteryl ester transfer protein (CETP), IDL acquires additional cholesteryl esters from high-density lipoprotein (HDL), and further processing by hepatic lipase converts IDL into cholesteryl ester-rich low-density lipoprotein (LDL).

Common research uses

Functionally, IDL plays a significant role in cholesterol delivery and lipid metabolism. Elevated IDL levels are independently associated with the progression of carotid atherosclerosis, ischemic heart disease, and stroke, with some evidence suggesting IDL may be even more atherogenic than LDL. Clinically, IDL measurement is gaining attention as a novel risk factor for cardiovascular disease and is used in research to better understand atherogenesis and lipid metabolism.

Common uses include calibrators and controls, cardiovascular research.