Metabolism & Endocrinology

Calibrators that don't consistently match patient population biology produce assays that drift. Iron-free and iron-loaded transferrin behave as different proteins and are each uniquely critical to meet cellular iron requirements. Recombinant apolipoproteins cannot match the number of complex biological functions of native lipoprotein particles.

Athens provides native human proteins for metabolism research: intact HDL, LDL, and VLDL particles, transferrin in defined iron saturation states, complete apolipoprotein panels, and HbA1c for diabetes diagnostics.

Our portfolio supports work from cellular-mechanism studies through IVD development.

Experience the Athens Standard:

≥98% purity for critical applications
Lot-specific CoAs with activity and purity data
95% same- or next-day shipping

Native Proteins for Metabolic Research

Metabolism research bridges basic science and clinical application – from understanding lipid transport mechanisms to developing diagnostic assays for diabetes and cardiovascular disease. Athens proteins support this full continuum.

Our proteins are purified from native human plasma to preserve the glycosylation, binding properties, and structural integrity that define biological function. For metabolism and endocrinology research, native structure matters.

What sets Athens apart for metabolism research:

Apolipoproteins and lipoproteins – Complete panel including ApoAI, ApoAII, ApoB, ApoCI, ApoC2, ApoC3, ApoE, plus HDL, LDL, VLDL, IDL, Lp(a), and oxidized LDL for cardiovascular and lipid metabolism studies.

Iron transport proteins – Transferrin (holo, apo, and partially saturated forms), Lactoferrin, and Ceruloplasmin for iron homeostasis and related metabolic research.

Vitamin and micronutrient carriers – GC Globulin (Vitamin D Binding Protein) and Retinol Binding Protein for studies of vitamin transport and endocrine function.

Diabetes and glycemic markers – HbA1c (Glycated Hemoglobin) for diagnostic calibration and diabetes research.

Nutritional status markers – Prealbumin (Transthyretin) and Albumin for nutritional assessment and metabolic studies.

Athens proteins have supported published research on adipocyte biology, cardiovascular disease mechanisms, and metabolic disease at leading institutions worldwide.

Cited in Metabolic Research

Athens proteins support published research on adipocyte biology, lipid metabolism, and cardiovascular disease.

Browse All Citations

*1. Kim, et al. Amblyomma americanum serpin 41 (AAS41) inhibits inflammation by targeting chymase and chymotrypsin. International Journal of Biological Macromolecules, 2020, 32320803. https://doi.org/10.1016/j.ijbiomac.2020.04.088

*2. Nielsen, et al. Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family. Nature Communications 13(1), 2022, 3033. https://doi.org/10.1038/s41467-022-30758-x

*3. Morejón García, et al. Generation and characterization of murine monoclonal antibodies against immunoreactive trypsinogen for newborn screening of cystic fibrosis. Analytical Biochemistry 591, 2020, 113569. https://doi.org/10.1016/j.ab.2019.113569

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Transport & Binding Proteins

Apolipoproteins, lipoproteins, transferrin, and vitamin carriers for lipid metabolism, iron transport, and endocrinology.

Glycoproteins & Acute Phase Proteins

HbA1c, Prealbumin, Haptoglobin, Alpha-1 Acid Glycoprotein – native markers for diabetes, nutrition, and metabolic status.

Enzymes & Protease Inhibitors

Ceruloplasmin, Catalase, and Dipeptidyl Peptidase IV – native enzymes for copper metabolism and metabolic regulation.

Antibodies & Immune Proteins

IgG, IgA, and IgM for metabolic assay development, autoimmune endocrinology research, and diagnostic controls.

Specialized Tissue Proteins

Angiotensinogen, Vitronectin, and plasma proteins for cardiovascular-metabolic research and cell culture applications.

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Need something unique?

Custom lipid panels? Calibrator-grade HbA1c? Bulk proteins for diagnostic manufacturing? We configure reagents to your specifications.

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Featured News & Resources

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Iron transport proteins – Transferrin (holo, apo, and partially saturated forms), Lactoferrin, and Ceruloplasmin for iron homeostasis and related metabolic research.

Vitamin and micronutrient carriers – GC Globulin (Vitamin D Binding Protein) and Retinol Binding Protein for studies of vitamin transport and endocrine function.

Diabetes and glycemic markers – HbA1c (Glycated Hemoglobin) for diagnostic calibration and diabetes research.

Nutritional status markers – Prealbumin (Transthyretin) and Albumin for nutritional assessment and metabolic studies.

Athens proteins have supported published research on adipocyte biology, cardiovascular disease mechanisms, and metabolic disease at leading institutions worldwide.