Inflammation isn't just one pathway—it's a web of proteases, inhibitors, complement factors, and immunoglobulins working in concert. Studying these systems requires reagents that capture that complexity.
Athens proteins are purified from human plasma, neutrophils, and other native sources to retain the post-translational modifications, glycosylation, and quaternary structures that drive biological function. When your experiment depends on enzymatic activity or native epitope recognition, recombinant proteins often fall short.
What sets Athens apart for immunology and inflammation research:
Neutrophil proteins with native activity – Myeloperoxidase (MPO), Proteinase 3 (PR3), Neutrophil Elastase, Cathepsin G, Defensins, and Lactoferrin purified with enzymatic activity intact. Our next-generation MPO maintains the native tetramer structure that recombinant versions cannot replicate.
Complement cascade components – C3c, C4c, C5, and regulatory proteins like C4b-Binding Protein and C1 Esterase Inhibitor for pathway studies and assay development.
Acute phase and inflammatory markers – CRP, Alpha-1 Antitrypsin, Haptoglobin, Ceruloplasmin, and Alpha-1 Acid Glycoprotein for inflammation monitoring and disease research.
Complete immunoglobulin portfolio – All IgG subclasses, IgA, IgM, IgE, plus fragments (Fc, Fab, Fc5u and u-chain) and specialty products like Rheumatoid Factor and Secretory IgA.
Our immunology reagents support research from basic mechanistic studies to IVD development—including ANCA diagnostics where native MPO and PR3 outperform recombinant alternatives.
