Neurological Disorders

Neurodegeneration, oxidative stress, protein misfolding – the mechanisms underlying neurological disorders are complex and interconnected. Studying them requires proteins that behave as they do in vivo.

Athens provides native human proteins relevant to neuroscience research: apolipoproteins implicated in Alzheimer's risk, antioxidant enzymes for oxidative stress studies, and neurological biomarkers for diagnostic development.

Our portfolio supports research from cellular mechanism studies through biomarker discovery and assay development. Athens' proteins are regularly used in animal studies (in vivo assays) and cell based assays (in vitro assays) to study neurological processes and disorders.

Experience the Athens Standard:

≥98% purity for critical applications
Lot-specific CoAs with activity and purity data
95% same- or next-day shipping

Native Proteins for Neuroscience Research

Neurological disorder research demands proteins that capture the complexity of the nervous system and its interactions with systemic biology. Athens proteins are purified from native human sources to preserve the structure and activity your experiments require.

Our neurological biomarkers and research reagents have supported published work on neurogenesis, Alzheimer's diagnostics, and oxidative stress – reflecting the breadth of applications these proteins enable.

What sets Athens apart for neurological research:

Apolipoproteins for neurodegeneration studies – ApoE and other apolipoproteins implicated in Alzheimer's disease risk, lipid metabolism in the CNS, and blood-brain barrier function.

Antioxidant enzymes – Superoxide Dismutase (SOD) and Catalase for oxidative stress research, including studies of ALS, Parkinson's, and other neurodegenerative conditions.

Cholinesterases – Butyrylcholinesterase (BChE) for Alzheimer's research and diagnostic development, with native enzymatic activity preserved.

Transport proteins linked to neurological disease – Transthyretin (prealbumin) for amyloidosis research, Ceruloplasmin for copper metabolism and Wilson's disease, and Hemopexin for heme regulation and neurogenesis studies.

Lipoproteins including oxidized LDL – For research on neuroinflammation, vascular contributions to cognitive impairment, and lipid-mediated neurotoxicity.

Cited in Neuroscience Research

Athens proteins support published research on neurogenesis, Alzheimer's diagnostics, and oxidative stress.

Browse All Citations

*1. Henrion, et al. Label-free quantification of host cell protein impurity in recombinant hemoglobin materials. Analytical and Bioanalytical Chemistry 416(2), 2024, 387–396. https://doi.org/10.1007/s00216-023-05024-8

*2. Saenkham-Huntsinger, et al. Copper resistance promotes fitness of methicillin-resistant Staphylococcus aureus during urinary tract infection. mBio 12(5), 2021, e0203821. https://doi.org/10.1128/mBio.02038-21

*3. Pakula, et al. An increase in reactive oxygen species underlies neonatal cerebellum repair. eLife 14, 2025, RP102515. https://doi.org/10.7554/eLife.102515

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Transport & Binding Proteins

ApoE and other apolipoproteins, lipoproteins, and oxidized LDL for Alzheimer's, neuroinflammation, and CNS lipid research.

Enzymes & Protease Inhibitors

SOD, Catalase, and Butyrylcholinesterase—native enzymes for oxidative stress, ALS, and Alzheimer's research.

Glycoproteins & Acute Phase Proteins

Transthyretin, Ceruloplasmin, Hemopexin, and Alpha-1 Acid Glycoprotein for amyloidosis and neurodegeneration studies.

Antibodies & Immune Proteins

TIgG subclasses and fragments for neurological assay development, autoimmune neurology research, and diagnostic controls.ext

Coagulation & Hemostasis Proteins

Plasminogen and plasmin for studies of the neurovascular unit, stroke, and blood-brain barrier integrity.

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Need something unique?

Custom specifications for neurological research? Bulk proteins for assay development? We configure reagents to your requirements.

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Featured News & Resources

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Apolipoproteins for neurodegeneration studies – ApoE and other apolipoproteins implicated in Alzheimer's disease risk, lipid metabolism in the CNS, and blood-brain barrier function.

Antioxidant enzymes – Superoxide Dismutase (SOD) and Catalase for oxidative stress research, including studies of ALS, Parkinson's, and other neurodegenerative conditions.

Cholinesterases – Butyrylcholinesterase (BChE) for Alzheimer's research and diagnostic development, with native enzymatic activity preserved.

Lipoproteins including oxidized LDL – For research on neuroinflammation, vascular contributions to cognitive impairment, and lipid-mediated neurotoxicity.