Where can I find the protein concentration?

The protein concentration of each product is listed on the Certificate of Analysis. This value is determined for each individual lot and reflects the actual concentration (mg/mL) of the material you received.

Where can I find the recommended storage conditions?

Storage conditions are listed on both the product datasheet and the Certificate of Analysis. These recommendations are based on internal stability assessments and are intended to maintain protein integrity and activity.

Where can I find reconstitution instructions for lyophilized products?

If your product is supplied lyophilized, recommended reconstitution instructions are provided on the product datasheet. These instructions outline the suggested solvent and handling tips to ensure optimal recovery and stability.

How should I store my product after reconstitution?

Unless otherwise stated on the datasheet or COA, we recommend aliquoting reconstituted material and storing at –80 °C to avoid repeated freeze–thaw cycles, which may impact protein stability and activity.

Prealbumin

Name: Prealbumin
SKU: 16-16-161801-500UG
Availability: InStock

PA, Transthyretin, Thyroxine Binding Prealbumin, ATTR, TBPA, TTR, PALB

The primary plasma protein responsible for transporting thyroxine, vitamin A, and retinol binding protein to target tissues.

Purity: ≥95% (SDS-PAGE)

Source: Human Plasma

Molecular Weight: 55 kDa

Form: Lyophilized

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Product Description

Role of protein in biology

Prealbumin, also known as transthyretin, is a serum protein present in plasma at approximately 30 mg per 100 ml. Synthesized primarily in the liver, prealbumin plays a vital role in transporting thyroxine (T4), vitamin A, and retinol-binding protein throughout the bloodstream. Its structure allows it to form complexes with these molecules, facilitating their delivery to target tissues. Prealbumin has a short biological half-life of about two days, making it a sensitive marker for acute changes in nutritional status and protein-energy malnutrition.

Common research uses

Clinically, low prealbumin levels are commonly observed in conditions such as viral hepatitis, cirrhosis, malnutrition, inflammation, acute kidney injury, and after surgical trauma. Decreased levels are associated with poor prognosis and increased mortality in critically ill and hospitalized patients. Prealbumin measurement is widely used to monitor nutritional interventions, assess liver function, and predict patient outcomes, especially in acute and chronic disease management.

Common uses include IVD Assay standards, calibrators and controls, therapeutics development, cardiovascular research, metabolism studies.