Albumin accounts for approximately 60% of total plasma protein and displays remarkable structural stability conferred by 17 disulfide bonds and conserved N-glycosylation. It is responsible for nearly 80% of plasma oncotic pressure, preventing vascular fluid loss. Beyond its structural role, albumin serves as a versatile carrier, binding and transporting a wide range of hydrophobic ligands—including fatty acids, steroids, thyroid hormones, calcium ions, and more than 90% of circulating drugs—through multiple dynamic binding sites. Its free Cys34 residue provides antioxidant activity by scavenging reactive oxygen species.